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Allulose a better non-caloric sweetener and possibly having GLP-1 inhibitor effects

Allulose a better non-caloric sweetener and possibly having GLP-1 inhibitor effects

Reposting an old 2014 article on sugar substitutes with a few updates. 2008 article on Honey also included.

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Yusuf JP Saleeby MD
Jun 04, 2025
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Allulose a better non-caloric sweetener and possibly having GLP-1 inhibitor effects
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Non-Caloric Sweeteners: Lots of choices, some of my recommendations for safe alternatives to sugar [updated article from 2014 with info on Allulose]

Natural Non-Caloric Sweeteners

By Yusuf Saleeby, MD (Dr. Saleeby OLD BLOG site) repost from 2014

It is widely appreciated that the over consumption of caloric sweeteners is a bad idea for a healthy diet. While some can tolerate simple sugars better than others, avoidance of too many simple carbohydrates in our SAD (Standard American Diet) is probably a good idea to avoid the eventualities of obesity, metabolic syndrome and type 2 diabetes (T2DM). Among the caloric sweeteners there are some good and bad choices, they will be enumerated here before listing some safe alternative non-caloric or low-caloric sweeteners. I will touch briefly on what is commercially available in the realm of synthetic non-caloric sweeteners and why they are not a smart choice. [much more beyond this line]

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