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Yusuf JP Saleeby MD's avatar

https://psp.sendowl.com/s/pha-education/functional-medicine-education/priority-health-academy-2025-educational-program-by-phhm for those interested in the 1-year PHA education only platform.

Discount on this $990 program is now $500 until July 15th when this offer ends. Those that pay for this program will have to sign a contract & NDA. We cover LYME among other reformed-Functional Medicine topics (r-FxMed).

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Yusuf JP Saleeby MD's avatar

Things to discuss would be the herbals.

Samento (Cats claw) and the combos of NUTRA BRL, BRT, etc. If we mention Banderol we should also refer to it as Otoba bark extract. Cryptolepis sanguinolenta and the article that showed it most effective.

Key Herbs & Their Potential Benefits for Lyme Disease:

Cryptolepis sanguinolenta (Ghanaian quinine): This herb demonstrates strong activity against both growing and non-growing forms of B. burgdorferi. In lab tests, it even caused complete eradication of the bacteria at a 1% extract concentration, while antibiotics like doxycycline and cefuroxime could not.

Polygonum cuspidatum (Japanese knotweed): Also shows strong activity against both growing and non-growing forms of the bacteria. It contains resveratrol, an antioxidant with anti-inflammatory properties that may help alleviate Lyme-associated inflammation.

Uncaria tomentosa (Cat's claw): Possesses anti-inflammatory and immune-boosting properties. It may help with common Lyme symptoms like joint pain and fatigue.

Artemisia annua (Sweet wormwood): This herb, used in traditional Chinese medicine, has anti-inflammatory and antimicrobial properties.

Scutellaria baicalensis (Chinese skullcap): Known for its anti-inflammatory and antimicrobial effects.

Juglans nigra (Black walnut): Valued for its anti-inflammatory, antifungal, antiparasitic, and antimicrobial properties.

Cistus incanus (Mediterranean rockrose): Has shown activity against Lyme disease bacteria in vitro.

Houttuynia

others.

If we had more time Dr. Moorcroft would tackle the Pharm stuff:

Piperacillin (newer agent being used for Lyme, IV or IM)

Arakoda (tafiquinine)

Doxy

Azithromycin

IVM

HCQ

Nitazoxanide

Mepron / atovaquone

Cipro

Metronidazole

Dapsone

Disulfiram

Minocycline

others.

Identification of Essential Oils with Strong Activity against Stationary Phase Borrelia burgdorferi (published in a journal)

A big one was:

Feng J, Leone J, Schweig S, Zhang Y. Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. Front Med (Lausanne). 2020 Feb 21;7:6. doi: 10.3389/fmed.2020.00006. PMID: 32154254; PMCID: PMC7050641.

Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi - PubMed (published in another journal)

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Yusuf JP Saleeby MD's avatar

Lyme Treatments Explained: Co-infections and Complex Cases

Video LINK:

https://imahealth.org/lyme-treatment/

Speakers: Dr. Yusuf (JP) Saleeby, Dr. Tom Moorcroft, Chris Jackman, FNP

Lyme disease is notoriously difficult to treat, but it’s even more complex than most realize. That’s because Lyme doesn’t always travel alone. Associated tick-borne co-infections like Bartonella and Babesia can mimic or mask Lyme symptoms, requiring different treatments to resolve. This reality turns Lyme treatment into a winding, uncertain road for patients and providers alike.

Luckily, we’ve enlisted some of the world’s top experts in Lyme and chronic disease to help demystify this debilitating condition. Join IMA Senior Fellow Dr. JP Saleeby as he hosts a practical conversation with Lyme specialist Dr. Tom Moorcroft and integrative nurse practitioner Chris Jackman. Together, they’ll break down what makes Lyme so persistent, how co-infections complicate recovery, and what successful treatment protocols can look like in the real world.

This is the third installment in IMA’s Lyme Disease series—an essential session for patients, practitioners, and anyone trying to make sense of this often-misunderstood chronic condition. Catch up with the previous episodes here:

Lyme disease isn’t just a rash, a round of antibiotics, and a return to normal life. For many patients, especially those with chronic or complex cases, the road to recovery is long, winding, and full of confusion. Why does treatment fail? Why do symptoms linger for months—or even years? And what role do lesser-known co-infections play?

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In this IMA webinar, three front-line Lyme experts: Dr. Tom Moorcroft, Chris Jackman, FNP, and IMA Senior Fellow Dr. JP Saleeby. They’ve come together to help chart a better path forward for Lyme patients. They speak not just as clinicians, but as seasoned listeners who are familiar with the suffering, misdiagnoses, and medical gaslighting their patients have endured.

The good news? There is hope. And it starts with understanding how Lyme really works, what makes chronic cases so tricky, and how to approach healing with precision, empathy, and an open mind.

Below is a breakdown of key takeaways from the conversation with quotes, context, and some straight talk from people who’ve seen it all.

Why Lyme Disease is Difficult to Treat—and How Co-infections Make It Worse

The Biggest Challenges Patients Face with Chronic Lyme

Personalized and Integrative Treatment Approaches are Essential

Finding the Right Provider for Lyme Treatment

How to Support the Body During Lyme Treatment

Common Lyme Treatment Questions Answered

tick that causes Lyme disease

1. Why Lyme Disease is Difficult to Treat—and How Co-infections Make It Worse

Lyme is complicated enough on its own. But in most serious cases, it’s not just Lyme.

Ticks can sometimes transmit a cocktail of infections: Babesia, Bartonella, Ehrlichia, and more. These “co-infections” interact, mask one another, and resist treatment differently. Standard tests often miss them. And many doctors don’t even know what to look for.

“These organisms have been around forever… These things have learned to really be alive in the human ecosystem… When the environment is inhospitable, like we’re doing a treatment protocol, they hide…” —Dr. Tom Moorcroft

bartonella on human skin

Bartonella

Even within Lyme itself, the bacteria are stealthy. They can lie dormant, form protective biofilms, and evade antibiotics, especially when treatment is delayed or incomplete.

“If you treat Lyme, you can miss Bartonella, and you can miss treating Babesiosis… It’s nearly impossible to treat Bartonella without concurrently treating Lyme. But you can treat Lyme without hitting Bartonella or Babesia…” —Dr. Tom Moorcroft

2. The Biggest Challenges Patients Face with Chronic Lyme

The hardest part of Lyme often isn’t the pathogen—it’s the medical system.

For Lyme Patients, it’s not uncommon to be told it’s “all in their head.” Many see dozens of doctors before receiving a proper diagnosis. Even then, they’re often dismissed if they don’t respond quickly to treatment.

“The hardest part isn’t necessarily the disease itself—it’s the stigma and isolation patients face when no one believes they’re sick… Treating Lyme isn’t the problem. We’re good at what we do. The problem is the stigma that comes with what the patients have to carry around to try to get better when everyone’s doubting them or saying they’re not sick.” —Chris Jackman, FNP

Chris Jackman, NP

Chris Jackman, FNP

That isolation takes more than just an emotional toll. It affects access to care, insurance coverage, family support, and leads patients’ to question their sanity.

3. Personalized and Integrative Treatment Approaches are Essential

There is no one-size-fits-all treatment for chronic Lyme. That’s not a drawback. It’s the point.

Effective care means listening, adjusting, and tailoring each plan to the individual. Chris Jackman emphasized that every patient should get a different plan, and that the plan can shift and be adapted quickly depending on patient response.

True healing incorporates not just medicine, but mindset. Dr. Moorcroft recalls how a mental shift helped him to deal with his own Lyme journey on the patient side:

“One of the things I found was if I worked on the mental and spiritual aspects of my life, reconnecting with my passions… it made a big difference… I remember one day just going, ‘My life sucks… I want to play outside with my dogs again… I want to enjoy the woods’… And as soon as I got excited about that and kept that in my heart, this started to change things.” —Dr. Tom Moorcroft

Dr. Tom Moorcroft

Dr. Tom Moorcroft

4. Finding the Right Provider for Lyme Treatment

Most doctors simply aren’t equipped to treat complex Lyme. Not because they don’t care—but because the system hasn’t prepared them.

Chris Jackman explained how a Lyme-literate provider can dramatically change the experience for patients:

“When you sit down and they start to explain their story… they’ll say, ‘You seem to be believing what I’m telling you.’ And I’m like, ‘Absolutely, I believe what you’re telling me. Why wouldn’t I?'” —Chris Jackman, FNP

Look for providers who:

Address co-infections alongside Lyme

Listen and tailor treatment as things evolve

Understand biofilms, immune dysregulation, and detox

And most importantly: believe your experience!

5. How to Support the Body During Lyme Treatment

Killing pathogens is only one piece of the Lyme puzzle. True recovery demands support for the entire body.

Nutrient-dense food: fuels repair and energy

Binders: mop up toxins from dying microbes and mold

Sleep and circadian support: critical for immune repair

Mitochondrial nutrients: rebuild energy capacity

Gentle movement: light activity, not intense workouts

Stress reduction: to support the gut-brain-immune axis

6. Common Lyme Treatment Questions Answered

You asked, our experts answered!

Can a low-oxalate diet help with chronic Lyme or inflammation?

Dr. Saleeby confirms that for certain people, yes, especially if they’ve had oxalate issues or metabolic imbalances.

How do you differentiate between mold illness and Lyme when symptoms overlap?

Dr. Moorcroft explains that history, testing, and treatment response are key.

Are there safe antimicrobials or herbals to use for children with Lyme?

Dr. Moorcroft affirms and names a few options like Japanese knotweed and Cat’s Claw, but notes that pediatric support requires expert guidance.

Can Babesia or Bartonella be passed congenitally from mother to child?

Confirmed by panel: there is documented vertical transmission, though it’s rare and under-researched.

Should patients with Lyme avoid vaccines?

Dr. Saleeby and Chris Jackman both express concern that immune dysregulation from vaccines can worsen chronic Lyme symptoms.

What lab tests are most helpful?

Dr. Moorcroft mentions using a combination of clinical judgment and specialty labs like IGeneX, Galaxy Diagnostics, and Armin Labs.

Can red light therapy support healing in Lyme patients?

All panelists say yes, especially for immune support, mitochondrial function, and mood.

A Lyme Treatment Roadmap, Not a Shortcut

Lyme treatment isn’t linear, and it’s seldom simple. But as our experts demonstrated, it is possible.

With open-minded practitioners, patient-tailored care, and ongoing support, healing happens every day. That’s why IMA continues to build resources, amplify honest science, and stand with patients and providers on their healing journey.

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More from IMA on Lyme:

Check out our ever-expanding Lyme Library for more:

🎥 Part 1: Diagnosing Lyme Disease

🎥 Part 2: The Hidden Battle with Co-Infections

📄 Beating Lyme Disease with Hyperthermia Treatment: Sophia’s Story

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Yusuf JP Saleeby MD's avatar

This was a wonderful EVENT and I am honored to have hosted Dr. Moorcroft and Chris our top FNP at Carolina Holistic Medicine. If you happened to miss this 3rd part of the LYME SERIES on IMA check back in a few days for the archived recording listed on the Weekly Webinar section of the IMAhealth.org website.

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